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Butylone has a methyl substitution at RN, a substitution that's shared with MDEA, ethylone, four-MEC, and selected other stimulants and entactogens. On top of that, butylone is made up of substitutions at R3 and R4 in the phenyl ring with oxygen teams. These oxygen teams are included right into a methylenedioxy ring through a methylene chain. Butyl